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《中国药理学与毒理学杂志》2019年09期

 
目录
大会报告
新时代中医药传承发展的机遇与挑战张伯礼;641-642
基于络病理论的中药新药研发吴以岭;642
中药多组分体内过程与药效关联研究的探索王广基;643
Targeting endothelial senescence by natural products to improve vascular healthValérie SCHINI-KERTH;643-644
Herbal formula enhances 5-fluorouracil activity through suppression of thymidylate synthaseLIU Hai-zhou;LIU Hui;ZHOU Zhi-yi;Robert A.PARISE;Edward CHU;John C.SCHMITZ;644-645
中西医结合研究诠释《神农本草经》有关灵芝的论述林志彬;645-646
做出中国新药的特色——小檗碱研究的思考蒋建东;646-647
Critical success factors for acceptance of multi-herbal Chinese medicine in EuropeWANG Mei;646-647
中药作用分子机制研究新策略王升启;647
中医药“异病同治”作用的分子生物学新解孙鹤;648
心脑缺血的防治策略与丹参及丹酚酸A的作用与机制杜冠华;王海港;宋俊科;张雯;刘成娣;刘楠楠;张莉;648-649
功能性胃肠病中药复方临床研究实践与思考张北华;唐旭东;649专题报告
从临床角度考虑维医药对溃疡性结肠炎的临床定位斯拉甫·艾白;阿不都外力·阿不都克里木;李治建;高莉;阿里甫·恩提;希尔艾力·吐尔逊;艾山江·司马义;胡拉木;阿不来提;650
基于“系统观”探讨中药复方研究的新思维和新方法陆茵;650-651
斑马鱼内毒素炎症模型建立及中药抗内毒素炎症研究周红玲;杨丽玲;刘东依;卢子滨;曹惠慧;刘俊珊;余林中;651
氧化与还原平衡:脑卒中神经保护和修复的治疗靶点及其在中医药应用沈剑刚;652
网络药理学与中成药再评价黄娜娜;孙蓉;653
中药外用疗效新机制苗明三;李孟艳;田硕;653-654
CA-30,an active fraction derived from Liuwei Dihuang Decoction,ameliorates cognitive deterioration via intestinal microbiomeZHOU Wen-xia;WANG Jian-hui;LEI Xi;ZHANG Xiao-rui;CHENG Xiao-rui;ZHANG Yong-xiang;654-655
西洋参茎叶总皂苷减轻模拟失重导致心肌重塑的作用研究孙慧媛;史大卓;655
有毒中药的毒效关系研究高月;655-656
中药有效成分的作用机制和物质基础张丹参;656
我国中药新药创制转化历程与药理学的作用赵军宁;鄢良春;戴瑛;华桦;曾瑾;李莉;尹竹君;张翼冠;657
青蒿素及其衍生物抗疟机制研究概况朱晓新;王继刚;657-658
Tetramethylpyrazine analogue T-006 promotes clearance of alpha-synuclein by enhancing proteasome activity in Parkinson disease modelsZHOU He-feng;SHAO Min;GUO Bao-jian;LI Chu-wen;LU Yu-cong;YANG Xuan-jun;LI Sheng-nan;LI Hai-tao;ZHU Qi;ZHONG Han-bing;WANG Yu-qiang;ZHANG Zai-jun;LU Jia-hong;LEE Ming-yuen Simon;658-659
调节性坏死与心脑损伤及女贞苷干预佘浪;张议月;刘斌;罗秀菊;彭军;659
丹红注射液治疗慢性稳定型心绞痛的靶点模块识别与多表型药理机制研究王忠;660
姜黄素在肿瘤治疗中的基础与临床研究和问题李学军;660-661
中药与天然药物的新药研究思路与实践刘建勋;661
来源于经典名方的中药新药高质量发展战略思考孙晓波;662
Pharmacophenomics and Fangjiomics:new pharmacological research paradigm in era of precision medicineDUAN Da-yue;YE Ling-yu;662-663
中药补益(保健)药理研究思考与思路吕圭源;663-664
中药复方大品种技术升级研究与培育的思路杨洪军;664青年论坛——青年学者
黄蜀葵花调控肠道菌群中尿毒素代谢通路干预慢性肾病进展的作用机制郭建明;665
Mechanisms of active fraction combination from Liuwei Dihuang Decoction(LW-AFC) on long-term potentiation impairment in vivoHUANG Yan;LI Dong;CHENG Bin;LIU Gang;ZHANG Yong-xiang;ZHOU Wen-xia;665
黄芪多糖RAP对巨噬细胞的激活及几种黄酮类化合物的干预作用李志鹏;666
创新降糖中药桑枝总生物碱调节肠-胰岛轴作用及机制初探刘率男;刘泉;李彩娜;环奕;刘志华;刘玉玲;谢明智;申竹芳;666-667
Reducing histone acetylation rescues cognitive deficits in mouse model of fragile X syndromeLI Yue;Michael E.STOCKTON;Brian E.EISINGER;ZHAO Ying-hua;Jessica L.MILLER;Ismat BHUIYAN;GAO Yu;WU Zhi-ping;PENG Jun-min;ZHAO Xin-yu;666
Myrrh extract alleviated ROS-mediated ferroptosis through regulating TXNIP/NLRP3 axis in ischemic strokeLIU Tian-long;WANG Wen-jun;DING Yi;WEN Ai-dong;ZHANG Ru-xue;667-668
基于粪便代谢组学的逍遥散抗抑郁作用机制刘晓节;吕梦;王雅泽;赵迪;赵思俊;李顺勇;秦雪梅;668
TCM-040抗心律失常作用及电生理机制苏敏;徐登峰;周璐恒;张晓佩;侯云龙;刘克剑;王宏涛;668-669
孟河医派特色炮制猪心血丹参及其他炮制品对大鼠脑缺血保护及PI3K/AKT信号通路的影响颜晓静;曹琰;黄玮;朱月琴;刘产明;曹震;张琪;669
CP-25 monotherapy and combined administration ameliorate progression of animal arthritis model by inhibition on GRK2 translocationYANG Xue-zhi;ZHAO Ying-jie;SU Su-li;WANG Chun;WU Yu-jing;ZHANG Ling-ling;CHANG Yan;WEI Wei;669-670
中药活性成分直接作用靶点“钩钓”技术的建立与应用曾克武;670
丹参多酚酸通过PI3K/Akt-JAK2/STAT3途径减轻大鼠脑缺血再灌注损伤张雯;宋俊科;杜冠华;670
复方中药塞络通对多发性脑梗死大鼠星形胶质细胞功能及脂笼蛋白2蛋白表达的影响张业昊;姚明江;刘建勋;671
Neuroprotection of total steroid saponins from Dioscorea zingiberensis C.H.Wright against transient focal cerebral ischemia-reperfusion injury in rats via its anti-inflammatory and anti-apoptotic effectsZHANG Xin-xin;WANG Xing-bin;ZHAN Guan-qun;GUO Zeng-jun;XIE Ren-ming;671
基于调控脑肠轴探索解毒化瘀汤改善阿尔茨海默病小鼠认知功能的机制张云龙;刘妍;徐评议;文磊;672
基于1H-NMR代谢组学及网络药理学方法研究罗勒黄酮类活性成分对ApoE-/-模型小鼠的影响周文婷;季志红;阿尔祖亚·多力空;阿地力江·萨吾提;艾尼瓦尔·吾买尔;672青年论坛——研究生
小檗碱通过调控溃疡性结肠炎肠道神经免疫炎症保护黏膜屏障损伤李恒;左建平;唐炜;673
山奈酚通过抑制神经炎症及保护血脑屏障而改善大鼠脑缺血再灌注神经功能李伟瀚;程笑;杨滢霖;刘漫;张姗姗;王月华;杜冠华;673
山楂叶黄酮类成分在糖脂代谢紊乱大鼠体内的代谢组学研究刘甜;周坤;王静静;韩伟;王栋梅;陈文君;马百平;郑晓辉;赵晔;674
千金藤素体外抗HSV-1的作用及机制初步研究刘鳐;唐琼;方洋;彭利霞;曾南;674
玉屏风散对小鼠胸腺上皮细胞介导的皮肤淋巴细胞功能的影响马丽;沈佳曼;郭文琴;高建莉;675
补骨脂酚通过上调上皮雌激素受体β和下调间质芳香化酶抑制大鼠良性前列腺增生齐雅馨;苗琳;焦婵媛;邵瑞;樊官伟;李小江;王跃飞;朱彦;张琚;高秀梅;675
基于网络药理学的大补脾汤治疗2型糖尿病的作用机制任伟钰;郑宜鋆;刘永琦;刘东玲;魏本君;676
Paeonol inhibits NLRP3 mediated inflammatory reaction in rat endothelial cells by elevating hyperlipidemic rats plasma exosomal miRNA-223SHI Xiao-yan;XIE Xian-mei;DAI Min;676-677
丹知青娥方抑制大鼠下尿路症状杨晓华;吴垚锌;贾思童;刘二伟;苗琳;高秀梅;677
理气活血颗粒对气滞血瘀证大鼠调节作用的血清代谢组学研究尹春园;孙明谦;刘建勋;史雅红;677
Anti-arthritis effect of berberine associated with regulating energy metabolism of macrophage through AMPK/HIF-1α pathwayYU Yun;ZHOU Jing;LU Hua-qiu;QI Jia-jia;WANG Ying;SONG Yi-ning;LIU Hao;WEI Fang;678
Effects of LW-AFC on anxiety-like behavior and immune function in corticosterone-induced miceZENG Ju;CHENG Xiao-rui;ZHOU Wen-xia;ZHANG Yong-xiang;678-679
Bufei Yishen granules suppress oxidative stress in rats with chronic obstructive pulmonary disease via Nrf2 signalingZHANG Lan-xi;TIAN Yan-ge;ZHU Li-hua;LIU Shuai;MA Jin-di;WU Ming-ming;LI Jian-sheng;679-680
Effect of astragaloside Ⅳ on lipid and glucose metabolism in acute myocardial infarction through PPARγ pathwayZHANG Qian;WANG Xiao-ping;WANG Yong;LI Chun;WANG Wei;680-681
芪苈强心胶囊通过PI3K/AKT/GSK3β信号通路延缓氧化应激损伤心肌细胞线粒体途径凋亡赵齐飞;刘焕;王晓雅;侯云龙;刘克剑;王宏涛;681
Identification of bioactive anti-angiogenic constitutes targeting tumor endothelial cells in Shenmai Injection using multidimensional pharmacokineticsZHONG Chong-jin;JIANG Chao;NI Sui-ying;WANG Qi-zhi;CHENG Ling-ge;WANG Huan;ZHANG Qi-xiang;LIU Wen-yue;ZHANG Jing-wei;LIU Jia-li;WANG Mu-lan;JIN Min;SHEN Pei-qiang;YAO Xue-quan;WANG Guang-ji;ZHOU Fang;681-682论文摘要
α-Hederin inhibits growth of lung cancer A549 cells in vitro and in vivo by decreasing c-Myc and HIF-1α dependent glycolysisFANG Cong;CHEN Lan-ying;LUO Ying-ying;CUI Ya-ru;ZHANG Ni;LIU Peng;ZHOU Meng-jing;XIE Yong-yan;LIU Ya-hui;682-683
Salvianolic acid A reduces endothelial-mesenchymal transition of HPAECsFANG Lian-hua;YUAN Tian-yi;CHEN Yu-cai;LYU Yang;DU Guan-hua;683
Total triterpenes from fruits of Chaenomeles speciosa(Sweet) Nakai protect against indomethacin-induced gastric mucosal injury: involvement of TFF1-mediated EGF/EGFR and apoptotic pathwaysFENG Min-lu;LI Xiao-mei;HE Hai-bo;XU Hai-yan;HE Yu-min;ZHANG Yuan-yuan;JIANG Wei-jie;WANG Jun-zhi;ZOU Kun;683-684
Jaridon 6, a natural autophagy inducer, anti-gastric resistance in vivo and in vitroFU Ling;HAN Bing-kai;WANG Tian-ye;WANG Jun-wei;LIU Xiao-li;WANG Jia-min;XIONG Ya-lan;LI Hui-ju;JIA Lu;KE Yu;LIU Hong-min;684-685
Pharmacological effects of ginsenoside Rg1 in neuropsychopharmacologyGAO Yan;CHU Shi-feng;ZHANG Zhao;ZHANG Lan;CHEN Nai-hong;685-686
Ginsenoside Rb1 attenuates adjuvant-induced arthritis in rats through inactivation of NF-κB signaling pathwayHAO Yan-fei;HUANG Ya-nan;ZHANG Lei-ming;WANG Mei-ling;WANG Xin-lin;WANG Yan-fang;FU Feng-hua;686
Nobiletin protects against metabolic syndrome by enhancing circadian rhythmsHE Bao-kun;686-687
Inhibition of self-renewal and differentiation of HT-29 cells-derived cancer stem-like cells by scutellarin via Hedgehog signaling pathwayLEI Nan;XIONG Si-hui;TAN Li;HE Man;ZHANG Meng;SUN Qiang;ZENG Sha;CHEN Li;XU Hai-bo;687
Total glucosides of paeony alleviates Sjogren syndrome through inhibiting inflammatory responses in miceLI Bin-bin;LIU Ge;LIU Rui;HE Shu-cheng;LI Xiang;HUANG Liang-liang;WANG Zi-yu;LI Yun-man;CHEN Yong-jian;YIN Hong;FANG Wei-rong;687-688
Effects of Ganoderma lucidum polysaccharides peptide on tumor metastasis in mice with sleep fragmentationLI Di-tian;ZHU Yin-an;LI Jia-yi;ZHANG Yi-meng;TAN Zhe-lun;LI Si-yan;PAN Yan;688
Paeoniflorin reduces cardiotoxicity of aconitine in H9c2 cellsLI J;ZHANG SH;HE D;WANG JF;LI JQ;689
Shenmai Injection attenuated doxorubicin-induced cardiac dysfunction via maintaining mitochondrial homeostasisLI Lin;LI Jing-hao;YANG Dong-li;LI Yu-hong;WANG Qi-long;689
Synthesis, hypoglycemic activity and toxicity study of vanadium oxide complex with genisteinLI Peng-shou;HE Chao-jun;LI Zi-yong;ZHANG Hai-ning;WANG Li-ye;690
Realgar transforming solution is involved of JNK, P38 MAPK pathway in down-regulating Ras/MAPK pathway in Caenorhabditis elegansLIU Dong-ling;ZHI De-juan;WAN Feng-qi;WANG Meng-qi;ZHOU Ting;BAI Yan-li;LI Hong-yu;690-691
EZH2 mediates mechanisms of AD20 on its inhibitory effects in PC3 cell proliferation and migrationLIU Shuai-shuai;LI Xue-jun;691
Antioxidation and active constituents analysis of flower residue of Rosa Damascena MillLIU Wen-ya;CHEN Lin-yu;HUANG Ying-ying;FU Ling;SONG Le-yuan;WANG Yun-yu;BAI Zhe;MENG Fang-feng;BI Yue-feng;691-692
Isochlorogenic acid A attenuates progression of liver fibrosis through regulating HMGB1/TLR4/NF-κB signaling pathwaysLIU Xin;KUANG Kai;MEI Dan;ZHANG Bo;692
Dehydrocostuslactone protects against oxygen-glucose deprivation/reperfusion-induced injury by inhibiting autophagy and apoptosis in PC12 cellsMA Hui-xia;HOU Fan;ZHANG Zheng-jun;CHEN Ai-ling;ZHU Ya-fei;Li Ting-ting;ZHANG Xin-hui;ZHAO Qi-peng;692-693
Protective effects of costunolide on mouse brain slice injury induced by oxygen glucose deprivation/reoxygenationMA Hui-xia;HOU Fan;CHEN Ai-ling;ZHANG Zhuan-zhuan;ZHU Ya-fei;ZHAO Qi-peng;693
Neocryptotanshinone protects cardiomyocyte hypoxia/reoxygenation-induced H9C2 cell injury through targeting RxRαMA Lin;CHEN Xu;SHAO Ming-yan;WANG Yong;693-694
Liuwei Dihuang soft capsules inhibits phenotypic conversion of VSMCs via up-regulating expression of myocardin by promoting interaction between ERα and SRC3MENG Qing-hai;YU Xi-chao;CHEN Qi;KONG Xue-yun;CHENG Peng;LI Yu;BIAN Hui-min;694-695
Mechanism of Danshen-Gegen in treating coronary heart disease based on network pharmacologyMA Yang;WANG Wen-jun;DING Yi;WEN Ai-dong;695
Oxyresveratrol suppresses proliferation and metastasis of hepatocellular carcinoma by inhibiting autophagy in vitro and in vivoSONG Ying-qi;WU Xi-cheng;LI Rong;JI Zhen-ni;MA Xiu-ying;XIONG Wen-bi;ZHANG Yuan-yuan;ZHOU Li-ming;695-696
Research progress in pharmacological actions of ginsenoside-Rg3SU Xiao-mei;ZHANG Dan-shen;696
Withaferin A arrested glioblastoma cells at G2/M phase and induced apoptosis through intrinsic pathwayTANG Qin;REN Li-wen;LIU Jin-yi;LI Wan;ZHENG Xiang-jin;WANG Jin-hua;DU Guan-hua;696-697
Ascorbic acid induces Ca2+-dependent necrosis mediated by reactive oxygen species in colorectal cancer cellsWANG Chang-xi;YU Jie;ZHONG Bing-ling;LU Jin-Jian;CHEN Xiu-ping;697
Whole transcriptome analysis identifies differentially regulated networks during proliferation inhibition and megakaryocytic differentiation of AML cell induced by DMAGWANG Long;LI Xiao-xuan;LIU Sha;YANG Jing;WU Jian-ming;697-698
Total flavonoids from Anchusa italica improves cardiac function and attenuates cardiac remodeling post-myocardial infarction in miceWANG Shou-bao;SONG Jun-ke;WANG Rong-rong;GAO Li;ZHANG Li;FANG Lian-hua;LYU Yang;DU Guan-hua;698-699
By regulating IP3/PKC/TRPV4 pathway hyperoside induces endothelium-dependent vasodilatation in rat basilar artery following four vessel occlusion ischemia reperfusionWANG Shu-fan;XU Hang-hang;CHEN Xiao-long;WANG Guo-dong;ZHENG Yong-qiu;HAN Jun;699
Regulation effects of rosemary(Rosmarinus officinalis Linn) on hepatic lipid metabolism in OA induced NAFLD ratsWANG Si-jian;CHEN Qian;LIU Meng-yang;YU Hai-yang;XU Jing-qi;WU Jia-qi;ZHANG Yi;WANGTao;699-700
Ginkgo Leaf Extract and Armillariella Mellea Powders Oral(银杏蜜环口服溶液) attenuates inflammation of microglia in habenular nucleus throughCX3CL1-CX3CR1 axis in post stroke depressionYAO Ming-jiang;FAN Xiao-di;YANG Bin;XU Li;SONG Wen-ting;WANG Guang-rui;DONG Xiao-xia;LIU Jian-xun;700-701
Ethno-medicinal study of Artemisia ordosica Krasch.(traditional Chinese/Mongolian medicine) extracts for treatment of allergic rhinitis and nasosinusitisXIAO Bin;ZHANG Na;ZHAO Na;HAN Xiao-yan;DU Guan-hua;701
Hesperetin induces glyoxalase 1 enhancement in SH-SY5Y cells cultured with high glucose via Nrf2/ARE activationZHANG Meng-ya;LIU Yao-wu;702
Effect of Astragaloside Ⅳ on lipid and glucose metabolism in acute myocardial infarction through PPARγ pathwayZHANG Qian;WANG Xiao-ping;WANG Yong;LI Chun;WANG Wei;702-703
Ligustroflavone reduces necroptosis in rat brain after ischemic stroke through targeting RIPK1/RIPK3/MLKLZHANG Yi-yue;LIU Wei-ning;LI Yue-qi;LUO Xiu-ju;PENG Jun;703
Ganoderma lucidum polysaccharide peptide alleviates hepatoteatosis via modulating bile acid metabolism dependent on FXR-SHP/FGFZHONG Dan-dan;YANG Bao-xue;703-704
中药注射剂的安全性及对策白埔;牛艺璇;任利文;王金华;肖斌;704-705
Gold nanostructures for anticancer drug deliveryZHU Xiao-ming;WAN Hong-ye;CHEN Jian-li;704
杜仲通过肠道菌群促进小鼠海马成体神经发生和学习记忆能力柴学军;吴永继;孙鹏浩;李凯凯;朱晓岩;赵善廷;705
基于网络药理学探讨连翘治疗呕吐作用机制陈斯琪;聂克;705-706
竹柏内酯E通过升高c-Jun促进肺癌细胞程序性细胞死亡蛋白配体1蛋白表达陈宇驰;黄沐阳;袁罗伟;陈修平;陆金健;706
6-姜酚对顺铂致化疗模型大鼠5-HT合成与代谢的影响程倩倩;冯晓娣;聂克;706
塞络通对OGD/R诱导hCMEC/D3细胞抗氧化损伤的作用机制范晓迪;707
缺血性脑卒中的炎症及抗炎药物的研究进展龚诗立;杨翠翠;胡朝英;张兰;707-708
UPLC-Q/TOF-MS based metabonomics revealed protective effect of Terminalia chebula extract on ischemic stroke ratsDING Yi;WEN Ai-dong;707
钙蛋白酶参与tau蛋白过度磷酸化及截断机制研究进展郭凯文;杨翠翠;张兰;708
基于模式生物斑马鱼模型的中药药效物质筛选技术及应用韩利文;孔浩天;史永平;张轩铭;张姗姗;李晓彬;刘可春;刘昌孝;708
毛酸浆活性成分PPB诱导人肝癌HepG2细胞凋亡何昕雅;张强;曹世杰;康宁;709
“良关系”化合物丹参素冰片酯抗神经炎症作用贾璞;廖莎;杨璐萌;赵晔;王世祥;郑晓晖;709
丹参饮的现代研究进展孔令雷;杜冠华;709
西藏当归总黄酮含量对比及体外抗氧化活性李捷;陈依春;崔海燕;张景瑜;郝婷婷;周自强;张海娇;巴桑次仁;色里玛;孙芳云;710
色氨酸2,3-双加氧酶介导炎症免疫调控的作用和研究进展李素素;杨雪枝;常艳;魏伟;710
丹参乙酸镁通过抑制NOX/VPO1通路阻止肺动脉高压大鼠右心室重构李涛;王婀莉;李年生;罗秀菊;刘斌;彭军;710-711
连翘花黄色素对秀丽隐杆线虫应激抗性的影响李玉英;李元通;张立伟;711
远志治疗抑郁症的药理研究李兆珍;李炜;张丹参;711-712
蟾皮水提物及其多肽抗乳腺癌作用及机制的初步研究刘旭;王彧;712
娃儿藤宁碱诱导肝癌细胞死亡及其作用机制刘宏伟;尹双双;王恺龙;包小妹;刘怡曼;王涛;于海洋;712-713
四氢姜黄素体外抗氧化作用刘俐;华桦;张可星;曾安琪;张敏;赵军宁;713
丹酚酸A在缺血性疾病中抗血小板作用及机制的研究进展刘楠楠;刘成娣;孔令雷;王淑美;杜冠华;713
眼舒液抗炎镇痛作用刘擎;崔海燕;李捷;郝婷婷;周自强;孙芳云;713-714
钩藤源活性化合物对急性应激模型小鼠认知功能的影响路畅;王陈;黄晏;周文霞;张永祥;赵勤实;714
山茱萸环烯醚萜苷以tau蛋白为靶点治疗阿尔茨海默病的研究马登磊;罗艺;李林;张兰;714-715
连翘叶水提物对乙酰胆碱酯酶和丁酰胆碱酯酶活性的抑制作用马红;杜会枝;715
舒血宁注射液新旧工艺对大鼠心肌缺血再灌注损伤保护作用的比较孟红旭;李磊;赵雨薇;马彦雷;史跃;刘建勋;715
大建中汤的临床应用及现代研究进展牛艺璇;孙波;白埔;苏长海;折占飞;肖斌;715-716
基于网络药理学探讨贞芪扶正颗粒治疗肝癌的潜在作用机制齐鹏;马清林;杜丽东;吴国泰;任远;716
小檗碱及其主要Ⅰ相代谢产物改善人肝癌Hep G2细胞胰岛素抵抗作用及机制初探曲明;曹世杰;康宁;邱峰;716
复方小续命汤防治阿尔茨海默病的物质基础探究申艳佳;庞晓丛;张宝月;杨冉;李莉;杜冠华;716-717
肾脏OAT1/3蛋白介导的玉屏风抗炎免疫药效配伍增效的药动学机制宋珏;闻泽强;李大朗;717
肺动脉高压动物模型研究进展孙姝婵;方莲花;杜冠华;717-718
Connexin43通过SIRT1-HIF1-α通路改善糖尿病肾小管间质纤维化的研究孙小鸿;黄凯鹏;黄河清;718
钩藤源活性化合物297和315对慢性不可预知温和应激模型小鼠的影响王陈;朱明好;黄晏;周文霞;张永祥;赵勤实;718
山楂果叶协同改善糖脂代谢紊乱的作用王静静;高聪;韩伟;高一铭;王栋梅;陈文君;马百平;郑晓晖;赵晔;719-720
Chrysanthemum extract alleviates acetaminophen-induced liver injury by inhibiting oxidative stress via AMPK pathway in rats王春丽;谢欣梅;庞晓斌;719
丹参提取物DS对化疗性结肠炎的治疗作用及机制王霖;王睿;杜冠华;720
紫堇总提物通过激活LDLR改善高脂诱导ApoE-/-小鼠脂代谢紊乱的机制王凌潇;马家乐;靳凤玉;刘孜渝;郑姣;720
龙胆苦苷对类风湿性关节炎的保护作用及其机制王美灵;张雷明;郝妍斐;王信林;王艳芳;傅风华;721
动物类有毒中药的毒与应用评价王诺琦;张莉;杨秀颖;杜冠华;721
葛根芩连汤中42个标志物的药代动力学研究揭示复方中小檗碱与甘草酸协同治疗糖尿病的作用机制王琦;乔雪;叶敏;721-722
槐定碱通过靶向MAPKAPK2抑制人结直肠癌的发展王蕊;刘宏伟;邵莹莹;王恺龙;尹双双;王涛;高秀梅;于海洋;722
BLE通过调节肠道菌群对化疗性肠黏膜炎小鼠的治疗作用王睿;王霖;王淑美;杜冠华;722-723
基于领域驱动数据挖掘的中医治疗气阴两虚证-药关系研究王文军;丁一;文爱东;723
黄连总生物碱与三七总皂苷组合物对糖尿病心肌病小鼠的作用王晓;刘博;张译心;王鑫;纪凤兰;丁涛;温福春;徐惠波;723
大株红景天胶囊常压耐缺氧和抗疲劳作用王艺博;肖智勇;周文霞;张永祥;724
丹参饮颗粒急性毒性的实验研究魏广义;孔令雷;王淑美;杜冠华;724
坚定中医药文化自信,加强理法方药的研究谢人明;724-725
基于网络药理学研究芍药苷治疗糖尿病周围神经病变作用机制邢琪昌;陈佳;李伟;刘征;刘湘;725
贝母瓜蒌散治疗支气管扩张症作用机制的网络药理学预测杨靖;沈心;王龙;吴建明;725-726
槲皮素对缺血性脑卒中大鼠血脑屏障的保护作用杨冉;申艳佳;李莉;杜冠华;726
小续命汤对急性脑缺血再灌注大鼠肠道屏障的影响及肠道菌群结构特征分析杨志宏;罗晓雅;沈晓玲;刘业菊;杜冠华;726
四种含药血清对小鼠B16黑素瘤细胞黑素合成及酪氨酸酶活性的影响叶梦怡;穆静;马惠昇;刘镭;727
葛根素缓解1型糖尿病大鼠骨骼肌萎缩殷琳;陈熙;李娜;贾伟华;王诺琦;侯碧玉;强桂芬;杨秀颖;杜冠华;727
7-去氧水仙环素通过靶向抑制Akt发挥抗肝癌作用尹双双;王蕊;邵莹莹;刘宏伟;王涛;于海洋;727-728
中药石蒜生物碱类抗肿瘤活性研究于海洋;728
马勃化学成分及药理作用的研究进展张健美;景永帅;张丹参;728-729
活血化瘀类中药生物效价检测方法的建立张莉华;郝瑞家;李孝庆;顾小盼;于彤;高云航;孙巍;张广平;叶祖光;马晓慧;729
蛇床子素抗癌作用机制及其剂型研究张楠;景永帅;张丹参;729-730
四氢姜黄素增强姜黄素抗乳腺癌作用机制初探张强;曹世杰;康宁;730
小檗碱通过诱导细胞抑制性自噬发挥抗胃癌作用张强;曹世杰;康宁;730-731
祛风湿强筋骨药对维甲酸致大鼠骨质疏松影响的实验研究张小丽;陈瑞明;李芳;范引科;姜姗姗;张涛;731
基于网络药理学的瓜蒌-薤白药对抗高脂血症的作用机制钟华;仇静文;吴鸿飞;戴敏;731-732
斑马鱼内毒素炎症模型构建及及中药抗内毒素炎症活性筛选周红玲;杨丽玲;刘东依;卢子滨;曹惠慧;刘俊珊;余林中;732
补骨脂素单次和重复给药药动学研究杨莉;于英莉;张玥;张盼阳;周昆;732-733
补骨脂素对大小鼠肝CYP450酶4种亚型表达的影响王昭昕;翟玉霞;于英莉;周昆;733
小花清风藤水提物对乙酰氨基酚致小鼠药物性肝损伤保护作用李建桥;李玉玲;胡建忠;赵东晓;殷丽强;贺海波;邹坤;733
异补骨脂素灌胃9天对雌性ICR小鼠肝毒性的初步研究宋蕾;毕亚男;于英莉;周昆;734
Bufei Yishen granules suppress oxidative stress in rats with chronic obstructive pulmonary disease via Nrf2 signalingZHANG Lan-xi;TIAN Yan-ge;ZHU Li-hua;LIU Shuai;MA Jin-di;WU Ming-ming;LI Jian-sheng;734-735
Protective effect of active ingredient of Ferula sinkiangensis on global cerebral ischemia-reperfusion miceZHANG Wen-qiang;MI Yan;XU Ji-kai;LI Ning;HOU Yue;735
LW-AFC调节神经元限制性沉默因子改善学习记忆作用机制的初步研究沈威;蒋宁;周文霞;736
LW-AFC对肿瘤坏死因子α致情绪障碍小鼠模型的作用郭彦飞;肖智勇;周文霞;张永祥;736
LW-AFC及其活性组分通过调节肠道菌群改善APP/PS1转基因小鼠学习记忆能力谢宗杰;程肖蕊;周文霞;张永祥;737
Effects of four components from Uncaria rhynchophylla on LTP impairment induced by lipopolysaccharideSUN Na;WANG Chen;HUANG Yan;ZHOU Wen-xia;ZHAO Qin-shi;737
Functional microbiomics reveals branched-chain amino acids depletion for alleviation of insulin resistance by berberineYUE Shi-jun;WANG Wen-xiao;YAN Dan;TANG Yu-ping;738
Sheng Jiang San, traditional multi-herb formulation, exerts anti-influenza effects in vitro and in vivo via neuraminidaseinhibition and immune regulationZHANG Tian-bo;XIAO Meng-jie;Chun-Kwok WONG;Ka-Pun CHRIS MOK;ZHAO Xin;TI Hui-hui;Pang-Chui SHAW;738-739
孟河医派苍术特色炮制品对脾虚证大鼠的药效作用曹琰;刘产明;朱月琴;黄玮;张琪;739
冬凌草甲素与西妥昔单抗联用通过线粒体途径及内质网应激途径协同诱导人喉癌细胞凋亡曹世杰;姜本科;康宁;739
靶向抑制JAK受体天然单体化合物筛选及在炎症性肠道疾病中的治疗作用和机制陈大朋;王亮;刘佳妮;冯盼盼;740
基于入脑成分的网络药理学方法探讨益气通络颗粒保护脑缺血再灌注损伤的作用机制姜云耀;刘楠;刘建勋;740
Multi-target mechanism of triphala in cardio-cerebral vascular diseases based on network pharmacologyLIU Tian-long;WANG Wen-jun;WEN Ai-dong;DING Yi;740-741
D-半乳糖衰老大鼠粪便代谢组学研究赵迪;赵思俊;秦雪梅;刘晓节;741
Total glucosides of paeony attenuates animal psoriasis induced inflammatory response through inhibiting STAT1 and STAT3 phosphorylationLI Bin-bin;HE Shu-cheng;LIU Rui;HUANG Liang-liang;LIU Ge;WANG Rui-xuan;YANG Zhuo-yue;LIU Xin-yi;LENG Ye;LIU Dan;YE Cheng-yu;LI Yun-man;CHEN Yong-jian;IN Hong;FANG Wei-rong;742
Mu-Xiang-You-Fang protects PC12 cells against OGD/R-induced autophagy via AMPK/mTOR signaling pathwayMA Hui-xia;CHEN Ai-ling;HOU Fan;LI Ting-ting;ZHU Ya-fei;ZHAO Qi-peng;742-743
纯化果实菠萝蛋白酶各组分对于结肠炎的缓解作用及其作用机制冯盼盼;陈大朋;王亮;刘佳妮;743
桑叶提取物通过调节肝线粒体融合分裂相关因子改善2型糖尿病大鼠的胰岛素抵抗高迎春;岳颖;周珺;马慧萍;张汝学;743
中药津力达颗粒通过抑制肝细胞焦亡来改善非酒精性脂肪肝郝媛媛;苏敏;高怀林;刘克剑;侯云龙;王宏涛;744
盐酸小檗碱抑制大鼠良性前列腺增生诱发的下尿路症状贾思童;苗琳;员小婷;焦婵媛;邵瑞;郝佳;常艳旭;樊官伟;张琚;耿强;Nuttapong WICHAI;高秀梅;744
木香70%乙醇提取物对缺氧小鼠肝保护作用靳婉君;郝颖;樊鹏程;杨林鹏;马慧萍;745
益肾强身丸和防衰益寿丸干预衰老小鼠作用研究宁一博;张雨婷;程龙;董世芬;孙建宁;745
中药单体与抗菌药物联合应用对抗泛耐药鲍曼不动杆菌的作用彭勤;王清会;孟千琳;凌保东;745-746
木香和沉香中调控乙酰胆碱酯酶活性成分的体外筛选史梦瑶;柴丽娟;郑童心;张晗;苗琳;746
通络清脑注射液通过减轻星形胶质细胞神经肿胀及抑制HMGB1/TLR4炎症通路对脑缺血再灌注大鼠脑水肿的影响田方泽;宋文婷;姚明江;徐立;任均国;王敏;刘建勋;746-747
葛根芩连丸对麻醉大鼠血压的影响杨梦琦;赵珊珊;谢人明;程敏;747
Antitumor effects and compatibility mechanism of Hedyotis Diffusa-Sculellaria Barbata herb pairZHAN Sheng;XU Huan-li;747-748
中药津力达颗粒通过提高棕色脂肪活性改善高脂饮食喂养小鼠的代谢紊乱张慧;周鸿儒;郝媛媛;刘妍;王宏涛;748
三黄泻心汤对麻醉大鼠血压的影响赵珊珊;杨梦琦;谢人明;程敏;748-749
Effect of Eurycoma longifolia stem extract on uric acid excretion in hyperuricemia miceBAO Rui-xia;LIU Meng-yang;WANG Dan;WEN Shao-shi;YU Hai-yang;ZHONG Yi;LI Zheng;ZHANG Yi;WANG Tao;749
Escin enhances anti-rheumatoid arthritis effects of low dose glucocorticoids through up-regulation of glucocorticoid receptorZHANG Lei-ming;HUANG Ya-nan;DU Yuan;WANG Mei-ling;WANG Xin-lin;WANG Yan-fang;HAO Yan-fei;WANG Tian;FU Feng-hua;749-750
基于肠道菌群发现用于治疗Treg缺失免疫缺陷病的新药何宝坤;750
丹参乙酸镁通过抑制NADPH氧化酶阻止肺动脉高压大鼠血管平滑肌细胞表型转化李涛;罗秀菊;王婀莉;李年生;张晓杰;刘斌;彭军;750-751
黄杨碱调节肝癌周期、自噬及转移的作用机制邵莹莹;尹双双;刘宏伟;王涛;于海洋;751
脑缺血再灌注神经细胞凋亡机制研究进展王冬睿;范蕾;751
诃子抑制草乌的排泄赵璐璐;邢海燕;王胜男;高原;谷超;李刚;751-752
Protective effect of sodium ferulate on cardiac hypertrophy in spontaneously hypertensive ratsCHEN Pan-pan;LI Zhong-li;JIN Feng;NIE Jing;GONG Qi-hai;SHI Jing-shan;DENG Jiang;752
金钗石斛总生物碱抑制海马tau蛋白的过度磷酸化李菲;刘波;石京山;龚其海;752
《中国药理学与毒理学杂志》简介3+753
第十二届全国中药与天然药物药理学术会议论文摘要641
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